High blood chloride: causes and symptoms

Do you know what high blood chloride is? Read the following article to get all the information you need about this condition.

High blood chloride: causes and symptoms

One of the electrolytes that are known to exist in the blood at specific concentrations is chloride. Its change leads to a group of symptoms that often go away by resetting these levels.

The most conspicuous signs and symptoms of hyperchloremia are discussed in the following article, along with recommendations for treatment:

High chloride in the blood 

High blood chloride is one of the electrolyte disorders that occur when blood chloride levels are higher than normal. Adults typically have chloride levels between 98 and 107 mEq/L.

It is noteworthy that when blood chloride levels increase, many of the functions that chloride performs in the body are disrupted, most notably the following ones:

  • Maintaining the acid-base balance.
  • regulating the body's fluid balance.
  • assisting in the production of digestive enzymes that support metabolism.
  • Transmission of nerve signals.

Symptoms of high blood chloride

If the increase in chloride in the blood is mild to moderate, it won't result in any symptoms that are noticeable, but if it persists for a long time, it may result in a number of symptoms, including the ones listed below:

  1. exhaustion.
  2. extreme thirst
  3. Dryness of the mucous membranes.
  4. Hypertension.
  5. muscle weakness

Causes of high blood chloride

High blood chloride levels can be caused by:

1. Pathological causes 

These reasons include: 

  • Having acute diarrhea .
  • having acute or long-term kidney disease.
  • Overuse of drugs containing bromide results in bromide poisoning.
  • Respiratory alkalosis - RA.

2. Medicinal reasons

It incorporates utilising the drugs listed below.

  • For a long time, carbonic anhydrase inhibitors (CAI) were used.
  • cortisone.
  • Nonsteroidal anti-inflammatory drugs.
  • Ammonium Chloride.
  • Estrogen.

3. Other reasons

Non-drug, non-drug-related causes include:

  • In the hospital, he received a lot of saline intravenously.
  • Drinking salted water.
  • Excessive intake of salty foods.

Diagnosis of high blood chloride

The approved diagnostic procedure for this condition is a chloride blood test (CBT), which is typically performed in conjunction with a series of routine blood tests or an electrolyte list examination (Electrolytes panel - EP).

In addition to this analysis, which is performed by drawing blood from a vein, the doctor might ask for a urine analysis because chloride can also be found in the urine.

Treatment of high blood chloride

Usually, the causes of high blood chloride are treated in order to alleviate it. If the cause is satisfactory, then the treatment is directed towards that disease.

Based on the diagnosis, the doctor may also recommend the following treatments for the patient:

  • use of medications for nausea and vomiting.
  • prescribing substitute medications in place of any previously prescribed drugs that increase chloride.
  • Get two to three litres of water each day.
  • Follow a nutritious, well-balanced diet.
  • Treat eating disorders,  if any.
  • Avoid consuming sources of caffeine.
  • Avoid using aspirin .
  • better diabetic patients' blood sugar management.

High acid metabolism in the blood 

In contrast to high blood chloride, hyperchloremic metabolic acidosis (HMA) develops when the body loses too much basic bicarbonate, which causes the blood to become acidic and triggers the body's reaction of trapping chloride inside it, causing it to rise.

One of its most frequent causes is certain types of renal tubular acidosis (RTA).

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